Adrenal is a chemical that is made from the adrenal glands of slaughtered cows, pigs, and sheep. Adrenal glands make certain hormones. People use it as a supplement. It can be taken by mouth, placed under the tongue (used sublingually) or injected into the veins (given intravenously).

By mouth, adrenal is used for low adrenal function, fatigue, stress, lowered resistance to illness, severe allergies, asthma, certain skin conditions such as eczema and psoriasis, and rheumatoid arthritis.

Some people put adrenal under the tongue for physical or emotional stress, poor stress tolerance, general fatigue, allergies, autoimmune disorders, depression, pain and swelling (inflammation), low blood pressure, low blood sugar, drug and alcohol withdrawal, and discontinuation of cortisone drugs.

Intravenously, adrenal has been used for treating low adrenal function, high levels of potassium in the blood, and ulcerative colitis, and for preventing miscarriage.