Conjugated linoleic acid (CLA) is a type of fat. Dairy and beef are major sources of CLA in the diet. Most CLA supplements are made from safflower oil.

Garcinia (Garcinia gummi-gutta) is a tree that grows in India and Southeast Asia. The fruit rind contains a chemical called hydroxycitric acid (HCA).

L-carnitine is a chemical that is made in the human brain, liver, and kidneys. It helps the body turn fat into energy. L-carnitine is important for heart and brain function, muscle movement, and many other body processes. The body can convert L-carnitine to other chemicals called acetyl-L-carnitine and propionyl-L-carnitine.

CLA might help reduce body fat deposits and improve immune function. The average diet supplies 15-174 mg of CLA daily.

HCA used in dietary supplements usually comes from garcinia. It might prevent fat storage, control appetite, and increase exercise endurance.

L-carnitine is used to increase L-carnitine levels in people whose natural level of L-carnitine is too low. Some people also use L-carnitine for conditions of the heart and blood vessels, serious kidney disease, and many other conditions.

People commonly take CLA by mouth for weight loss. It is also often used for bodybuilding and fitness.

People commonly use garcinia for obesity, athletic performance, joint pain, and many other conditions.